The New England Patriots will need to take down one of the top teams in the NFL if they want to book their trip to the 2022 NFL playoffs. They likely need a win against Buffalo on Sunday to make the playoffs, as they would need the Steelers and Dolphins to also lose if they come up short. New England is currently a 7.5-point underdog to Buffalo in the latest Week 18 NFL odds at Caesars Sportsbook. The Patriots were able to keep their playoff hopes alive with a 23-21 win against Miami on New Year’s Day. Which Week 18 NFL lines should you target with your Week 18 NFL bets? Before you make any Week 18 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season.  

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 18. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 18 NFL picks at SportsLine.

Top Week 18 NFL picks

After simulating every game 10,000 times, the model is high on the Seattle Seahawks (-6.5) to cover against the Los Angeles Rams. Seattle needs some help from Detroit on Sunday night in order to make the playoffs, but the Seahawks are still alive heading into the final week of the regular season. Their game will be played prior to Detroit’s trip to Green Bay later in the day, so the Seahawks are not going to be lacking motivation in this matchup. 

They were able to get back on track following a three-game losing streak, blowing out the Jets in a 23-6 final last week. Quarterback Geno Smith threw a pair of touchdown passes in the first half, while running back Kenneth Walker III rushed for 133 yards. Walker had a 60-yard run on the first play of the game to set the tone, as Seattle recorded its third-most rushing yards (198) in a game this season. 

This is a favorable matchup for Seattle, as Los Angeles has nothing to play for on Sunday afternoon. The Rams are coming off another blowout loss, getting crushed by the Chargers in a 31-10 decision. SportsLine’s model does not expect them to be competitive down the stretch on Sunday, as the Seahawks are covering the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 18 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model’s NFL Week 18 best bets and parlay at SportsLine

What are the model’s top Week 18 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 18 NFL best bets from a model on a 160-113 run on its top-rated picks, and find out.

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