TIAA Bank Field will be the center of attention in the NFL on Saturday night in Week 18. The Jacksonville Jaguars will host the Tennessee Titans in the regular season finale on both sides, with the winner claiming the AFC South title. Jacksonville is 8-8 this season after a four-game winning streak, and the Jaguars will also win the division title with a tie against Tennessee. The Titans are 7-9 overall and 4-4 on the road, with Tennessee seeking a third straight division title.

Kickoff is at 8:15 p.m. ET in Jacksonville. Caesars Sportsbook lists Jacksonville as a 6.5-point home favorite, while the over/under, or total number of points Vegas thinks will be scored, is 40 in the latest Titans vs. Jaguars odds. Before locking in any Jaguars vs. Titans picks, make sure you check out the NFL predictions and betting advice from the SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season.

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has broken down Titans vs. Jaguars from every angle and locked in its NFL Week 18 picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting trends for Jaguars vs. Titans:

  • Titans vs. Jaguars spread: Jaguars -6.5
  • Titans vs. Jaguars over/under: 40 points
  • Titans vs. Jaguars money line: Jaguars -278, Titans +222
  • TENN: Titans are 5-2-1 against the spread in road games
  • JAX: Jaguars are 4-2 against the spread in home games
  • Titans vs. Jaguars picks: See picks at SportsLine

Featured Game | Jacksonville Jaguars vs. Tennessee Titans

Why the Titans can cover 

Tennessee enters with a three-day rest advantage, which could come in handy when game-planning without starting quarterback Ryan Tannehill. The Titans do have offensive strengths to lean on, including an elite red zone efficiency mark of 65.9%. Tennessee is also above-average in ball security with only 15 turnovers this season, and the running game is strong. The Titans are keyed by Derrick Henry, who ranks No. 3 in the NFL with 1,429 rushing yards despite missing last week’s game.

Henry is No. 2 with 95.3 rushing yards per game, 1,808 yards from scrimmage, and 13 rushing touchdowns. He also dominates the Jaguars consistently, averaging 105.3 rushing yards per game in 12 career appearances against Jacksonville. He has the second-most rushing yards of any NFL player ever against the Jaguars. See which side to back here.

Why the Jaguars can cover 

In the Week 14 meeting between these teams, quarterback Trevor Lawrence threw for more than 360 yards and created four touchdowns. Lawrence ranks in the top 10 in passing yards (3,901), completions (367), passing touchdowns (24), passer rating (95.4), interception rate (1.4%) and sack rate (4.5%). He has 14 passing touchdowns against only two interceptions in the last eight games.

The Titans rank last in the league in passing yards allowed and second-to-last in passing touchdowns allowed. Jacksonville is in the top 12 in total offense, scoring offense, first downs, passing yards, interception avoidance, rushing yards, yards per carry and rushing touchdowns this season. See which side to back here

How to make Jaguars vs. Titans picks

The model has simulated Saturday’s Titans vs. Jaguars matchup 10,000 times. The model is leaning Under the total, predicting 37 combined points. The model also says one side of the spread cashes well over 50% of the time. You can only see the model’s pick at SportsLine

So who wins Titans vs. Jaguars on Saturday? And which side of the spread cashes well over 50% of the time? Visit SportsLine right now to see which side of the Jaguars vs. Titans spread you should be all over Saturday, all from the model on a 160-113 roll on its top-rated NFL picks, and find out.

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